Is a quantification of factor VII in serum,  (formerly known as proconvertin) is one of the proteins that causes blood to clot in the coagulation cascade. It is an enzyme (EC 3.4.21.21) of the serine protease class. Abnormal measurements of factor VII may be associated with congenital deficiency of factor VII, disseminated intravascular coagulation (DIC), fat malabsorption, liver disease (such as cirrhosis). Vitamin K deficiency, Warfarin (Coumadin) use. The trait is Experimental Factor Ontology identifier EFO_0004619 (factor VII measurement).