Is a quantification of CD40 ligand,  primarily expressed on activated CD4+ T lymphocytes. Protein function - mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching.1 Publication
Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway. The trait is Experimental Factor Ontology entry EFO_0004790 (CD40 ligand measurement). Also known as: CD154 ligand measurement.