HIV-associated neurocognitive disorder (HAND) remains a common complication of HIV infection in the combination antiretroviral therapy (ART) era. Although modern ART has substantially improved life expectancy and reduced the incidence of HIVassociated dementia (HAD), milder forms of HAND remain prevalent, including asymptomatic neurocognitive impairment (ANI) and mild neurocognitive disorder (MND). The overall
prevalence of HAND is 30–50% among unselected HIV-infected
persons. The phenotype is HIV-associated neurocognitive disorder (EFO_0007948, an Experimental Factor Ontology term). Also known as: HAND.