EFO_0008537 (anti-topoisomerase-I-antibody-positive systemic scleroderma) is a sub-type of systemic scleroderma characterised by the presence of antibodies to topoisomerase-1 protein. Also known as: ATA-positive systemic scleroderma, ATA-positive systemic sclerosis, anti-topoisomerase-1-antibody-positive systemic scleroderma, anti-topoisomerase-1-antibody-positive systemic sclerosis, anti-topoisomerase-I-antibody-positive systemic sclerosis.