A parasitic infection caused by Trypanosoma cruzi. It is transmitted by insect bites. It is characterized by an acute and chronic phase; in the acute phase patients may have fever, malaise, and swelling at the site of the insect bite. In the chronic phase patients develop hepatosplenomegaly, lymphadenopathy, cardiomyopathy and arrhythmias. [ NCI ]. The disease is Experimental Factor Ontology id EFO_0008559 (American trypanosomiasis). Also known as: Chagas disease, Chagas' Disease, South American trypanosomiasis, Trypanosoma cruzi Infection, human American trypanosomiasis.