EFO_0010248 (spinocerebellar ataxia, autosomal recessive, 27) is a form of spinocerebellar ataxia, a clinically and genetically  heterogeneous group of cerebellar disorders due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR27 is a progressive disease characterized by gait difficulties, eye movement abnormalities, dysarthria, and difficulty writing. Some patients may lose independent ambulation. Additional features include spasticity of the lower limbs and cognitive impairment.