mitochondrial dna depletion syndrome 8b (mngie type) (EFO_0022093) can be described as follows. Mitochondrial DNA depletion syndrome-8B is characterized by ophthalmoplegia, ptosis, gastrointestinal dysmotility, cachexia, peripheral neuropathy, and brain MRI changes, known as the MNGIE phenotype (Shaibani et al., 2009). Also known as: MTDPS8B.