A hereditary disease characterized by childhood onset HYPERTENSION, hypokalemic alkalosis, and low RENIN and ALDOSTERONE secretion. It results from a defect in the activity of the 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 enzyme which results in inadequate conversion of CORTISOL to CORTISONE. The build up of unprocessed cortisol to levels that stimulate MINERALOCORTICOID RECEPTORS creates the appearance of having excessive MINERALOCORTICOIDS. The disease is Experimental Factor Ontology term EFO_1000817 (apparent mineralocorticoid excess syndrome). Also known as: Mineralocorticoid Excess Syndrome, Apparent, syndrome of apparent mineralocorticoid excess (disorder).