Experimental Factor Ontology id EFO_1000952 (glycogen storage disease VIII) is an x-linked recessive hepatic glycogen storage disease resulting from lack of expression of phosphorylase-b-kinase activity. Symptoms are relatively mild; hepatomegaly, increased liver glycogen, and decreased leukocyte phosphorylase are present. Liver shrinkage occurs in response to glucagon. Also known as: Glycogen Storage Disease Type VIII, Glycogen storage disease type VIII (disorder), glycogen storage disease type VIII, glycogenosis type VIII, hepatic glycogen phosphorylase kinase deficiency (disorder).