EFO_1001471 (Merkel cell skin cancer) is a carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245). Also known as: MCC, Merkel Cell Cancer, Merkel Cell Carcinoma, Merkel Cell Tumor, Merkle Tumors.