Systemic capillary leak syndrome (SCLS) is a severe systemic disease due to increased capillary permeability, characterized by episodes of hypotension, edema and hypovolemia. The disease is Systemic capillary leak syndrome (Experimental Factor Ontology identifier EFO_1001477). Also known as: Capillary hyperpermeability syndrome, Capillary leak syndrome, Clarkson disease, Idiopathic capillary leak syndrome, SCLS.