A hypermotility disorder of the ESOPHAGUS that is characterized by spastic non-peristaltic responses to SWALLOWING; CHEST PAIN; and DYSPHAGIA. The disease is Experimental Factor Ontology identifier EFO_1001785 (diffuse esophageal spasm). Also known as: Esophageal Spasm, Diffuse, diffuse spasm of esophagus, dyskinesia of esophagus, symptomatic diffuse esophageal spasm.