Macular telangiectasia type 2 is a rare neurovascular degenerative retinal disease. MacTel cases typically present at 40–60 years of age with abnormal right-angled juxtafoveolar capillaries and parafoveal telangiectasias. MacTel is an uncommon disease with a 0.0045–0.1% population prevalence and no obvious sex bias. Retinal lesions typically co- present with MacTel, including retinal transparency, outer retinal and choroidal neovascularization, lamellar holes or foveal cysts, photoreceptor dysfunction, minimal exudation, yellow–white parafoveal crystals, and retinal pigment epithelium (RPE) pigmen- tation abnormalities and atrophy. Central vision impairment and decreased visual acuity are the usual clinical outcomes. MacTel is a bilateral disease, but asymmetry of the eyes for disease severity and presence of lesions is possible. The lesions also occur in 0.06–1.18% of the general population. The disease is macular telangiectasia type 2 (EFO_1002009). Also known as: MacTel, idiopathic juxtafoveal retinal telangiectasis type 2.