Intense feelings of nervousness, tension, or panic often arise in response to interpersonal stresses. There is worry about the negative effects of past unpleasant experiences and future negative possibilities. Individuals may feel fearful, apprehensive, or threatened by uncertainty, and they may also have fears of falling apart or losing control. The phenotype is Anxiety (Human Phenotype Ontology identifier HP_0000739). Also known as: Anxiousness, Excessive, persistent worry and fear.