An invasive adenocarcinoma of the colon characterized by the presence of malignant glandular epithelial cells which contain prominent intracytoplasmic mucin (signet ring cells). The signet ring cells constitute more than 50% of the malignant cells. The disease is MONDO_0002495 (colon signet ring cell adenocarcinoma). Also known as: colon signet Ring cell adenocarcinoma, colonic signet Ring adenocarcinoma, colonic signet Ring cell adenocarcinoma, signet Ring cell adenocarcinoma of colon, signet Ring cell adenocarcinoma of the colon, signet Ring cell colon adenocarcinoma.