A squamous cell carcinoma of the bladder arising from metaplastic epithelium. It represents less than 10% of bladder carcinomas. The exception is the Middle East along the Nile Valley, where it represents the most common form of carcinoma because of the endemic nature of schistosomiasis. Bladder squamous cell carcinoma is often associated with long-standing chronic inflammation of the bladder and usually has a poor prognosis. The diagnosis of squamous cell carcinoma of the bladder should be reserved for those tumors that are predominantly keratin forming. The disease is bladder squamous cell carcinoma (MONDO_0002760). Also known as: bladder epidermoid carcinoma, bladder squamous cell cancer, epidermoid carcinoma of bladder, epidermoid carcinoma of the bladder, epidermoid carcinoma of the urinary bladder, epidermoid carcinoma of urinary bladder, squamous cell carcinoma of bladder, squamous cell carcinoma of the bladder.