Monarch Disease Ontology term MONDO_0002999 (central nervous system germinoma) is a malignant germ cell tumor arising from the central nervous system. It is composed of uniform cells resembling primitive germ cells. These cells have large, vesicular nuclei, prominent nucleoli and a clear, glycogen-rich cytoplasm. Additional features are lymphoid or lymphoplasmacytic infiltrates and, less frequently, scattered syncytiotrophoblastic giant cells. (Adapted from WHO). Also known as: central nervous system germinoma (disease), germinoma of CNS, germinoma of central nervous system, germinoma of the CNS, germinoma of the central nervous system.