periosteal chondrosarcoma (Monarch Disease Ontology identifier MONDO_0003680) can be described as follows. A chondrosarcoma arising from the surface of bone. It is characterized by a lobulated growth pattern, high mitotic activity, myxoid stroma formation, and necrotic changes. It occurs in adults. Clinical presentation includes pain, and sometimes swelling. Also known as: chondrosarcoma (disease) of periosteum, juxtacortical chondrosarcoma, juxtacortical chondrosarcoma (morphologic abnormality), periosteum chondrosarcoma (disease).