herpes simplex infectious disease (MONDO_0004609) is a group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.). Also known as: Herpesvirus hominis disease, Simplexvirus caused disease or disorder, Simplexvirus disease or disorder, Simplexvirus infectious disease.