A malignant neoplasm involving the submandibular gland. The disease is submandibular gland cancer (MONDO_0004724). Also known as: cancer of submandibular gland, malignant neoplasm of submandibular gland, malignant neoplasm of submaxillary gland, malignant submandibular gland neoplasm, malignant tumor of submandibular gland, malignant tumor of the submandibular gland, malignant tumour of submandibular gland, malignant tumour of the submandibular gland.