Monarch Disease Ontology term MONDO_0004952 (Hodgkins lymphoma) is a heterogeneous group of malignant lymphoid neoplasms of B-cell origin characterized histologically by the presence of Hodgkin and Reed-Sternberg (HRS) cells in the vast majority of cases. There are two distinct subtypes: nodular lymphocyte predominant Hodgkin lymphoma and classical Hodgkin lymphoma. Hodgkin lymphoma involves primarily lymph nodes. Also known as: HL, Hodgkin disease, Hodgkin lymphoma, Hodgkin's Disease, Hodgkin's disease, Hodgkin's lymphoma.