MONDO_0005008 (colorectal adenocarcinoma) can be described as follows. The most common type of colorectal carcinoma. It is characterized by the presence of malignant glandular epithelial cells invading through the muscularis mucosa into the submucosa. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma. Also known as: adenocarcinoma of large bowel, adenocarcinoma of large intestine, adenocarcinoma of the large bowel, adenocarcinoma of the large intestine, colorectal (colon or rectal) adenocarcinoma, colorectum adenocarcinoma, large bowel adenocarcinoma, large intestine adenocarcinoma.