MONDO_0005178 (osteoarthritis) is a noninflammatory degenerative joint disease occurring chiefly in older persons, characterized by degeneration of the articular cartilage, hypertrophy of bone at the margins and changes in the synovial membrane. It is accompanied by pain and stiffness, particularly after prolonged activity. Also known as: degenerative arthritis, degenerative joint disease, hypertrophic arthritis, osteoarthrosis, osteoarthrosis and allied disorder.