A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss). The disease is osteoporosis (MONDO_0005298). Also known as: bone mineral density variation QTL, osteoporosis, osteoporosis, postmenopausal, osteoporosis, postmenopausal, susceptibility, osteoporosis, susceptibility to.