primary biliary cholangitis (MONDO_0005388, a Monarch Disease Ontology term) (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology characterized by injury of the intrahepatic bile ducts that may eventually lead to liver failure. Also known as: Hanot syndrome, PBC, biliary liver cirrhosis, cholestatic cirrhosis, chronic non-suppurative destructive cholangitis, chronic nonsuppurative destructive cholangitis, primary Bilary cirrhosis (PBC), primary biliary cirrhosis.