Hereditary cerebral hemorrhage with amyloidosis (HCHWA) describes a group of rare familial central nervous system disorders characterized by amyloid deposition in the cerebral blood vessels leading to hemorrhagic and non-hemorrhagic strokes, focal neurological deficits, and progressive cognitive decline eventually leading to dementia. The disease is MONDO_0005620 (cerebral amyloid angiopathy). Also known as: HCHWA, dutch hereditary cerebral amyloid angiopathy, hereditary cerebral haemorrhage with amyloidosis - Dutch type, hereditary cerebral hemorrhage with amyloidosis - Dutch type.