bone giant cell tumor (Monarch Disease Ontology identifier MONDO_0005674) is a benign but locally aggressive tumor that arises from the bone and is composed of mononuclear cells admixed with macrophages and osteoclast-like giant cells. It usually arises from the ends of long bones or the vertebrae. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint. Also known as: GCT of bone, Osteoclastoma, benign, benign bone giant cell tumor, benign bone giant cell tumour, giant cell neoplasm of bone, giant cell tumor of bone, giant cell tumor of bone (morphologic abnormality), giant cell tumor of bone NOS (morphologic abnormality).