Monarch Disease Ontology term MONDO_0006068 (ACTH-producing pituitary gland adenoma) is an adenoma of the pituitary gland that produces corticotropin. The vast majority of cases are associated with Cushing disease. Clinical manifestations include truncal obesity with thin extremities, thinning of the skin, osteoporosis, and a tendency to bruise easily. Silent or hormonally non-functioning ACTH producing adenomas have also been described. They produce symptoms of a mass-related lesion. Also known as: ACTH producing pituitary gland adenoma, ACTH secreting adenoma of pituitary, ACTH secreting adenoma of the pituitary, ACTH-producing pituitary adenoma, ACTH-secreting adenoma of pituitary, ACTH-secreting adenoma of pituitary gland, ACTH-secreting adenoma of the pituitary, ACTH-secreting adenoma of the pituitary gland.