A gastrointestinal stromal tumor that arises from the colon or rectum. The majority of cases have spindle cell morphology. Gastrointestinal stromal tumors of the colon are usually advanced upon detection and tend to have a poor prognosis; gastrointestinal stromal tumors of the rectum usually have an aggressive clinical course. The disease is colorectal gastrointestinal stromal tumor (MONDO_0006159, a Monarch Disease Ontology id). Also known as: colorectal (colon or rectal) gastrointestinal stromal tumor (gist), colorectal (colon or rectal) gastrointestinal stromal tumour (gist), colorectal gastrointestinal stromal tumor (gist), colorectal gastrointestinal stromal tumour (gist), colorectal gist.