An adenocarcinoma arising from the pancreas. It is characterized by the presence of relatively uniform malignant cells which form acinar patterns. It usually occurs during adulthood. Signs and symptoms include abdominal pain, weight loss, nausea, and diarrhea. It may metastasize to regional lymph nodes and the liver. A minority of patients develop lipase hypersecretion syndrome. This syndrome may be seen in patients with liver metastases and it is characterized by excessive secretion of lipase in the serum, polyarthralgia, and subcutaneous fat necrosis. The disease is pancreatic acinar cell carcinoma (MONDO_0006346, a Monarch Disease Ontology id). Also known as: Pancreatic acinar cell cancer, acinar cell adenocarcinoma of pancreas, acinar cell adenocarcinoma of the pancreas, acinar cell carcinoma of pancreas, acinar cell carcinoma of the pancreas, carcinoma of pancreatic acinar cell, pancreas acinar cell adenocarcinoma, pancreatic acinar cell adenocarcinoma.