An adenocarcinoma arising from the thyroid gland showing only limited evidence of follicular cell differentiation. Microscopically, the adenocarcinoma cells are arranged in insular, solid, and trabecular patterns. There is associated necrosis, and vascular invasion. The prognosis depends on the tumor stage, complete or partial surgical removal of the tumor, and the degree of response to radioactive iodine therapy (adapted from WHO Tumors of Endocrine Organs, IARC Press, Lyon 2004). The disease is poorly differentiated thyroid gland carcinoma (MONDO_0006382, a Monarch Disease Ontology term). Also known as: insular carcinoma, poorly differentiated carcinoma of the thyroid gland, poorly differentiated carcinoma of thyroid gland, poorly differentiated thyroid carcinoma, poorly differentiated thyroid gland cancer, thyroid gland poorly differentiated carcinoma.