MONDO_0006490 (vaginal squamous cell carcinoma) is a squamous cell carcinoma arising from the vagina. Human papillomavirus infection is associated with the development of vaginal intraepithelial neoplasia and invasive squamous cell carcinoma. Signs and symptoms include painless bleeding, postcoital bleeding, and urinary tract symptoms. Morphologically it resembles squamous cell carcinomas in other anatomic sites. Radiation therapy is the preferred treatment for most cases. The prognosis is related to the stage of the disease. Also known as: carcinoma of vagina squamous cell, epidermoid carcinoma of the vagina, epidermoid carcinoma of vagina, epidermoid cell carcinoma of the vagina, epidermoid cell carcinoma of vagina, squamous cell carcinoma of the vagina, squamous cell carcinoma of vagina, vagina epidermoid carcinoma.