Any one of a group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. Common causes include deficiencies in glucose-6-phosphate isomerase; pyruvate kinase; and glucose-6-phosphate dehydrogenase. The disease is congenital nonspherocytic hemolytic anemia (Monarch Disease Ontology identifier MONDO_0006506). Also known as: HNSHA, anemia, congenital, nonspherocytic hemolytic, hereditary nonspherocytic hemolytic anaemia, hereditary nonspherocytic hemolytic anemia.