An acute inflammatory process that leads to necrosis of the pancreatic parenchyma. Signs and symptoms include severe abdominal pain, nausea, vomiting, diarrhea, fever, and shock. Causes include alcohol consumption, presence of gallstones, trauma, and drugs. The disease is MONDO_0006515 (acute pancreatitis). Also known as: acute pancreatitis (disorder) [ambiguous], pancreatitis, acute.