Monarch Disease Ontology identifier MONDO_0006639 (adrenal cortex carcinoma) is a rare, usually large (greater than 5cm), malignant epithelial tumor arising from the adrenal cortical cells. Symptoms are usually related to the excessive production of hormones, and include Cushing's syndrome and virilism in women. Common sites of metastasis include liver, lung, bone, and retroperitoneal lymph nodes. Advanced radiologic procedures have enabled the detection of small tumors, resulting in the improvement of the 5-year survival. Also known as: ACC, Adenoid Cystic Carcinoma, adenocarcinoma, adrenocortical, malignant, adrenal cortex adenocarcinoma, adrenal cortical adenocarcinoma, adrenal cortical carcinoma, adrenal cortical carcinoma (morphologic abnormality), adrenocortical carcinoma.