Stenosing tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons in the first dorsal wrist compartment. The presenting symptoms are usually pain and tenderness at the radial styloid. The cause is almost always related to overuse injury or is associated with rheumatoid arthritis. The disease is MONDO_0006721 (de Quervain disease). Also known as: radial styloid tenosynovitis, tenosynovitis, de Quervain's.