acrokeratosis verruciformis (MONDO_0007048) is a rare genetic skin keratinization disorder with an autosomal dominant mode of inheritance. It is characterized by numerous flesh-colored warty papules on the back of the hands, medial aspect of the feet, knees, and elbows. Also known as: AKV of Hopf, Hopf disease, acrokeratosis verruciformis of Hopf.