gastroesophageal reflux disease (MONDO_0007186) is a chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa. Also known as: GERD, GERD - gastro-esophageal reflux disease, Gastresophageal reflux, acid reflux, gastro-esophageal reflux, gastroesophageal reflux.