Cherubism is a rare, self-limiting, fibro-osseous, genetic disease of childhood and adolescence characterized by varying degrees of progressive bilateral enlargement of the mandible and/or maxilla, with clinical repercussions in severe cases. The disease is MONDO_0007315 (cherubism). Also known as: CRBM, familial fibrous dysplasia of the jaws, familial multilocular cystic disease of the jaws.