Renal coloboma syndrome (RCS) is a genetic condition characterized by optic nerve dysplasia and renal hypodysplasia. The disease is renal coloboma syndrome (MONDO_0007352). Also known as: CAKUT with or without ocular abnormalities, Papillo-renal syndrome, coloboma of optic nerve with renal disease, congenital anomalies of the kidney and urinary tract with or without ocular abnormalities, optic coloboma, vesicoureteral reflux and renal anomalies, papillo-renal syndrome, optic nerve coloboma with renal disease, papillorenal syndrome, renal-coloboma syndrome with macular abnormalities.