A chronic tubulointerstitial nephropathy that affects people in certain rural areas along the Danube river in the Balkans. It leads to end-stage renal disease. The disease is Balkan nephropathy (MONDO_0007416, a Monarch Disease Ontology term). Also known as: Balkan endemic nephropathy, Chinese herb endemic nephropathy, Danubian endemic familial nephropathy, aristolochic acid nephropathy, endemic nephropathy.