Dentatorubral pallidoluysian atrophy (DRPLA) is a rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I). It is characterized by involuntary movements, ataxia, epilepsy, mental disorders, cognitive decline and prominent anticipation. The disease is dentatorubral-pallidoluysian atrophy (MONDO_0007435). Also known as: DRPLA, Dentatorubropallidoluysian atrophy, Naito-Oyanagi disease, haw River syndrome.