multiple epiphyseal dysplasia type 1 (MONDO_0007561) (MED 1) is a form of multiple epiphyseal dysplasia that is characterized by normal or mild short stature, pain in the hips and/or knees, progressive deformity of extremities and early-onset osteoarthrosis. Specific features to MED 1 include a more pronounced involvement of hip joints and gait abnormality and a shorter adult height. MED1 is allelic to pseudoachondroplasia with which it shares clinical and radiological features. The disease follows an autosomal dominant mode of transmission. Also known as: COMP multiple epiphyseal dysplasia (disease), EDM1, MED1, Polyepiphyseal dysplasia type 1, epiphyseal dysplasia, multiple, type 1, multiple epiphyseal dysplasia (disease) caused by mutation in COMP.