A rare premalignant hyperproliferative gastropathy characterized by massive overgrowth of foveolar cells in the gastric lining, resulting in large gastric folds, and manifesting with epigastric pain, nausea, vomiting, peripheral edema and, less commonly, anorexia and weight loss. The disease is MONDO_0007652 (gastric mucosal hypertrophy). Also known as: MENETRIER disease, Menetrier Disease, Menetrier disease, Menetrier's disease, Ménétrier disease, familial giant hypertrophic gastritis, giant hypertrophic gastritis, giant rugal hypertrophy of stomach.