A neurologic disorder caused by defective metabolism of the neurotransmitters in the brain. It is characterized by repeated involuntary movements (motor tics) and uncontrollable vocal sounds (vocal tics). The symptoms are usually manifested before the age of eighteen. The disease is Tourette syndrome (MONDO_0007661, a Monarch Disease Ontology term). Also known as: Guinon's disease, Tourette disease, Tourette's syndrome, motor-verbal tic disorder, psychogenic tics.