Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by autonomic failure (cardiovascular and/or urinary), parkinsonism, cerebellar impairment and corticospinal signs with a median survival of 6-9 years. The disease is Monarch Disease Ontology id MONDO_0007803 (multiple system atrophy). Also known as: MSA, Shy-Drager syndrome, multisystem atrophy.