Ichthyosis hystrix of Curth-Macklin (IHCM) is a rare type of keratinopathic ichthyosis that is characterized by the presence of severe hyperkeratotic lesions and palmoplantar keratoderma (PPK). The disease is MONDO_0007808 (ichthyosis hystrix of Curth-Macklin). Also known as: Curth-Macklin type ichthyosis hystrix, IHCM, Ichthyosis Hystrix, Curth Macklin Type, ichthyosis HYSTRIX, Curth-Macklin type, ichthyosis histrix, curth-macklin type, ichthyosis hystrix, Curth Macklin type, ichthyosis hystrix, Curth-Macklin type.