Superficial epidermolytic ichthyosis (SEI) is a rare keratinopathic ichthyosis (KI) characterized by the presence of superficial blisters and erosions at birth. The disease is superficial epidermolytic ichthyosis (MONDO_0007813, a Monarch Disease Ontology term). Also known as: SEI, bullous type ichthyosis, ichthyosis bullosa of Siemens.