Langer-Giedon syndrome, also known as trichorhinophalangeal syndrome type 2, is a very rare, genetic, multiple congenital anomaly disorder characterized by bone abnormalities, distinctive facial features, multiple exostoses, and intellectual disability. The disease is trichorhinophalangeal syndrome type II (MONDO_0007874). Also known as: Langer-Giedion syndrome, deletion 8q24.1, monosomy 8q24.1, trichorhinophalangeal dysplasia type II, trichorhinophalangeal syndrome type 2.