Legg-Calve-Perthes disease (MONDO_0007885) can be described as follows. A hip region disease that is characterized by uni- or bilateral avascular necrosis (AVN) of the femoral head in children. In a small percentage of cases, mutations in the COL2A1 gene were found to be responsible. Also known as: Calve - Perthes' disease, Legg Calvé Perthes Disease, Legg-CALVE-Perthes disease, Legg-Calve-Perthes symptom, Legg-Calve-Perthes syndrome, Legg-Calvé-Perthes disease, Legg-Perthes disease, Osteochondrosis of the capital femoral epiphysis.